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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome

Fig. 4

Human and feline ASCs increase interleukin-8 (IL-8) but not transforming growth factor beta (TGFβ) above baseline peripheral blood mononuclear cell (PBMC) production. Production of IL-8 by feline ASCs is significantly increased regardless of contact with stimulated PMBCs (a). IL-8 is also produced by stimulated human ASCs with (P = 0.08) and without contact (b). Production of TGFβ by activated mesenchymal stem cells (MSCs) is not altered from baseline expression regardless of contact in both cats (c) and humans (d). Data presented as mean and standard error. *P < 0.05, **P < 0.01, ***P < 0.001. ConA concanavalin A, PHA leucoagglutinin

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