Fig. 6

Vascular remodeling was evaluated by von Willebrand factor (vWF) immunostaining. a Representative perfusion MRI map showing normal, hyper-, and hypoperfusion areas in (i) the vehicle group and (ii) the treatment group at 28 days after stroke. The yellow frame presents the field of view selected in the analysis of vWF immunostaining. Higher magnification images of vWF staining are shown in correlated normal CBF, hyperperfusion, and hypoperfusions areas of the two groups. Scale bar = 100 μm. b Mean intensity of vWF fluorescence in ROI were quantified (n = 6, mean ± SEM). *P < 0.05, versus the PBS vehicle; ^## P < 0.01, ^### P < 0.001, ^#### P < 0.0001, versus normal perfusion of same group. hUCB human umbilical cord blood, MNC mononuclear cell