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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars

Fig. 4

Scaffolds promote the long-term retention of UC-MSCs in uterine scars. a, b Uterine scars were transplanted with CM-Dil-labelled UC-MSCs or scaffold/UC-MSCs. At day 30 post-transplantation, uterine tissues containing the scarred areas were collected, embedded and sectioned. Cell nuclei were stained with DAPI (blue). UC-MSCs were tracked by the red fluorescence of CM-Dil under a fluorescence microscope. c-f The sections were stained with anti-vimentin antibody and observed under a fluorescence microscope (green). Scale bars, 20 μm. g Statistical analysis of the number of cells positive for CM-Dil and vimentin counted from six randomly selected fields per section under a magnification of × 600. * P < 0.05 and ** P < 0.01. UC-MSCs umbilical cord-derived mesenchymal stem cells

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