Fig. 4
Nerve fibres in cross sections of the distal colon. Distribution of fibres labelled by neuron-specific anti-β-tubulin (III) antibody in colon sections from sham-treated, TNBS-only, 1 × 105 MSC-treated, 1 × 106 MSC-treated and 3 × 106 MSC-treated guinea-pigs at 72 hours post induction of colitis (a-e). Scale bars = 100 μm. β-tubulin (III)-IR fibres were quantified in the mucosa (f) and muscular (g) layers of the colon. ### P < 0.001 when compared to sham-treated guinea-pigs, ***P < 0.001 when compared to TNBS-only administered guinea-pigs, ^^^P < 0.001 when compared to 1 × 105 MSC-treated guinea-pigs. n = 4/group/time point. IR immunoreactive, MSCs mesenchymal stem cells, TNBS 2,4,6-trinitrobenzene sulfonic acid