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Table 2 Changes in the peripheral blood cell proportion before and after insulin and AHSCT treatments

From: Immune response after autologous hematopoietic stem cell transplantation in type 1 diabetes mellitus

 

Insulin-only group

AHSCT group

Insulin-0M

Insulin-12M

AHSCT-0M

AHSCT-12M

WBC (×109/L)

6.01 ± 1.00

5.96 ± 1.38

5.74 ± 1.78

4.16 ± 1.17*

Monocyte (%)

6.37 ± 2.13

7.12 ± 1.49

6.91 ± 1.39

7.40 ± 0.32

Lymphocyte (%)

37.80 ± 8.46

42.39 ± 5.90

42.94 ± 5.55

33.64 ± 7.01*

CD3+CD4+ T cell (%)

41.96 ± 6.44

43.57 ± 8.70

39.89 ± 8.25

30.59 ± 5.30**

CD3+CD8+ T cell (%)

31.73 ± 7.99

27.65 ± 7.93

31.49 ± 5.72

30.83 ± 11.34

TCR(α/β) (%)

69.94 ± 6.43

71.95 ± 4.72

72.56 ± 6.46

57.90 ± 10.49*

  1. Data presented as mean ± SD
  2. AHSCT autologous hematopoietic stem cell transplantation, 0 M at baseline, 12 M at 12 months
  3. *P < 0.05, **P < 0.01, compared with the Insulin-12 M group
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Stem Cell Research & Therapy

ISSN: 1757-6512