Skip to main content
Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Autophagy mediates the beneficial effect of hypoxic preconditioning on bone marrow mesenchymal stem cells for the therapy of myocardial infarction

Fig. 8

Evaluation of fibrosis and heart function after myocardial infarction (MI). a Representative Masson’s trichrome staining revealed left ventricular fibrosis 4 weeks after MI (magnification 4×). Quantitative analysis of the fibrotic area (b) and infarct wall thickness (c). Histograms illustrating heart function parameters: left ventricular end-diastolic diameter (LVEDd, d), left ventricular end-systolic diameter (LVESd, e), left ventricular ejection fraction (f) and left ventricular fractional shortening (g). Data are expressed as means ± SEM; n = 5; *p < 0.05. 3-MA 3-methyladenine, HPC MSCs hypoxic preconditioned mesenchymal stem cells, LV left ventricle, NPC MSCs normal preconditioned mesenchymal stem cells, Sham sham-operated, siRNA small interfering RNA

Back to article page