Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway

Fig. 5

RNF43 regulates the Wnt/β-catenin pathway in GCSLCs. a Western blot of RNF43 expression in cancer cell lines. RNF43 OE leads to downregulation of β-catenin, a key protein in Wnt/β-catenin pathway, as well as reduction of TCF4, C-myc, and Lgr5 expression. b Xenograft tumor tissues were analyzed for RNF43, β-catenin, and Sox-2 expression by immunohistochemistry. Scale bar, 10 μm (black) and 25 μm (red) (Color figure online). OE overexpression

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512