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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway

Fig. 3

Pharmacological effect of bFGF, TGF-β1, and bFGF + DAPT in repairing wound healing and scaring. Full-thickness dermal wounds were induced in rabbit ears and treated by saline (control), bFGF, bFGF + DAPT, and TGF-β1 respectively. a Representative rabbit ear from each group taken on post-injury days 0, 7, 14, 30, and 60. b Wound areas for each group. The computation was that the indicated area was divided by the initial area. Results represent means ± SEM. *P < 0.05 compared with control value (n = 10). c Scar indexes for each group. The computation was that the thickness difference of the scar minus the adjacent normal skin was divided by the adjacent normal skin. Results represent means ± SEM. *P < 0.05 compared with control value (n = 10). d days, bFGF basic fibroblast growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512