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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway

Fig. 5

Relationships of bFGF and the Notch1/Jagged1 pathway and differentiation of ESCs in healed skin analyzed by immunofluorescence. a, b, c Representative Brdu/Jagged1, Brdu/Notch1, and Brdu/Hes1 double-positive cells in healed skin and the percentage of the positive cells to total cells in healed skin of each group on post-injury day 60. d Representative Brdu/α-SMA double-positive cells in healed skin and the percentage of the positive cells to total cells in healed skin of each group on post-injury day 60. Error bars represent SEM. Student’s t test, *P < 0.05 compared with control value (n = 10). Scale bar, 50 μm. bFGF basic fibroblast growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512