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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

Fig. 1

Clinical background of study patients. a Clinical data of AAA patients; data are reported as mean ± standard deviation (n = 12). b Evaluation of calcium content within the aortic wall: representative non-contrast angio-CT acquisition of AAA wall corresponding to scores 1 (upper panel) and 3 (lower panel). c Alizarin Red staining of healthy vs AAA tissue sections showed  the presence of calcium depositions only in the affected aorta (black stars), reflecting a diffuse localization within the whole arterial wall with more intensive staining at the media level. d Serum levels of MMP-9 protein in AAA patients compared with pooled sera from healthy donors. The assay was executed in duplicate and data are reported as mean ± standard deviation of two independent assays. *p < 0.05. AAA abdominal aortic aneurysm, CV cardiovascular, CT computed tomography, LDL low density lipoprotein, HDL high density lipoprotein, MMP-9 matrix metalloproteinase-9

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