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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

Fig. 5

Impaired endothelial differentiation in AAA-MSCs. a Representative pictures of ha-MSCs and AAA-MSCs after culture in Matrigel for 6 hours. Scale bar: 50 μm. b Morphometric analysis of neo-vessels performed on Matrigel-differentiated MSCs after 6 hours, according to total tubule length and number of branching points and total tubes (Wimasis Image Analysis software). Results are expressed as fold changes relative to ha-MSC control; statistical analysis was performed by two-way ANOVA with multiple comparisons among all experimental conditions. *p < 0.05. ha-MSC healthy aortic MSC, AAA-MSC abdominal aortic aneurysm MSC, MSC mesenchymal stem cell, ctrl control, VEGF vascular endothelial growth factor

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