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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton’s jelly and bone marrow-derived mesenchymal stem cells

Fig. 1

Growth characteristics of BM-MSCs and WJ-MSCs. Graph a depicts the days (mean ± 1standard deviation) for population doubling (PD) of BM-MSCs (n = 18) and WJ-MSCs (n = 18) through passages (P). Graph b depicts the results of the optical density (mean ± 1 standard deviation) corresponding to the number of metabolically active cells over a 21-day culture using the MTT assay in MSCs at P2. Graph c depicts the individual long-term growth curves of BM-MSC and WJ-MSC cultures. Every cell passage is indicated by a point and the number of cumulative PDs was calculated based on the ratio of cells seeded versus cells harvested per passage. Comparison between BM- and WJ-MSCs for PD and MTT was performed by the two-way analysis of variance. Abbreviations: BM-MSCs bone marrow-mesenchymal stem cells, MTT 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide, WJ-MSCs Wharton’s jelly-mesenchymal stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512