Cytokinesa
| WJ-MSC culture supernatants (n = 18) | BM-MSC culture supernatants (n = 18) |
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| P2 | P6 | P10 | P2 | P6 | P10 |
P value |
FLT3L (ng/mL) | 13.79 ± 0.75 | 14.35 ± 1.24 | 13.74 ± 0.87 | 13.77 ± 0.96 | 14.70 ± 6 2.33 | 13.43 ± 0.45 | N.S. |
SDF1-α (ng/mL) | 1189.00 ± 380.40 | 1159.00 ± 401.00 | 1032.00 ± 269.00 | 2074.00 ± 1247.00 | 1607.00 ± 698.00 | 1369.00 ± 420.60 | 0.0012 |
G-CSF (ng/mL) | 108.30 ± 100.70 | 578.00 ± 409.80 | 388.00 ± 360.00 | N.D. | N.D. | N.D | <0.0001 |
GM-CSF (ng/mL) | 12.19 ± 9.46 | 145.20 ± 135.60 | 37.70 ± 13.58 | N.D. | N.D. | N.D. | 0.0002 |
- Cytokine measurements have been performed by means of an enzyme-linked immunosorbent assay (ELISA). Comparisons in cytokine levels between WJ-MSCs and BM-MSC supernatants through passages (P) P2-P6-P10, were performed by two-way analysis of variance and the statistically significant P values are shown
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Abbreviations: WJ-MSCs Wharton’s jelly-mesenchymal stem cells, BM-MSCs bone marrow-derived mesenchymal stem cells, P passage, FLT3L FMS-like tyrosine kinase 3 ligand, SDF-1α stromal cell-derived factor-1α, G-CSF granulocyte colony-stimulating factor, GM-CSF granulocyte-macrophage colony -stimulating factor, N.S. no statistically significant difference, N.D. not detected
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aThe data are expressed as means ± 1 standard deviation