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Table 2 Cytokines in MSC culture supernatants

From: Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton’s jelly and bone marrow-derived mesenchymal stem cells

Cytokinesa WJ-MSC culture supernatants
(n = 18)
BM-MSC culture supernatants
(n = 18)
  P2 P6 P10 P2 P6 P10 P value
FLT3L (ng/mL) 13.79 ± 0.75 14.35 ± 1.24 13.74 ± 0.87 13.77 ± 0.96 14.70 ± 6 2.33 13.43 ± 0.45 N.S.
SDF1-α (ng/mL) 1189.00 ± 380.40 1159.00 ± 401.00 1032.00 ± 269.00 2074.00 ± 1247.00 1607.00 ± 698.00 1369.00 ± 420.60 0.0012
G-CSF (ng/mL) 108.30 ± 100.70 578.00 ± 409.80 388.00 ± 360.00 N.D. N.D. N.D <0.0001
GM-CSF (ng/mL) 12.19 ± 9.46 145.20 ± 135.60 37.70 ± 13.58 N.D. N.D. N.D. 0.0002
  1. Cytokine measurements have been performed by means of an enzyme-linked immunosorbent assay (ELISA). Comparisons in cytokine levels between WJ-MSCs and BM-MSC supernatants through passages (P) P2-P6-P10, were performed by two-way analysis of variance and the statistically significant P values are shown
  2. Abbreviations: WJ-MSCs Wharton’s jelly-mesenchymal stem cells, BM-MSCs bone marrow-derived mesenchymal stem cells, P passage, FLT3L FMS-like tyrosine kinase 3 ligand, SDF-1α stromal cell-derived factor-1α, G-CSF granulocyte colony-stimulating factor, GM-CSF granulocyte-macrophage colony -stimulating factor, N.S. no statistically significant difference, N.D. not detected
  3. aThe data are expressed as means ± 1 standard deviation