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Table 2 Patient characteristics and demographic data at the time of enrollment

From: Safety and tolerability of autologous bone marrow mesenchymal stromal cells in ADPKD patients

Patient number

1

2

3

4

5

6

Sex (m/f)

F

M

M

M

F

F

Age (years)

45

37

39

28

51

54

Race

Caucasian

Caucasian

Caucasian

Caucasian

Caucasian

Caucasian

Educational level

Graduate studies

Completed high school

Graduate studies

Graduate studies

Completed high school

Completed high school

Marital status

Married

Married

Married

Married

Married

Married

Number of children

2

1

2

0

2

2

Employment

Full-time employment

Full-time employment

Part-time employment

Full-time employment

Retired

Homemaker

Diagnosis due to

Incidental imaging

Screening

Screening

Screening

Screening

Screening

BMI (kg/m2)

29.38

26.45

26.18

35.51

24.34

23.41

Blood group

O+

A-

A+

O+

B+

B+

BP sitting position (mm Hg)

135/80

115/79

110/70

131/70

133/73

127/83

eGFR (ml/min/1.73 m2)

25

32

25

25

25

29

GFR DTPA SCAN

23

41.6

24

28

26

32.83

Serum creatinine (mg/dl)

2.3

2.3

2.8

3.0

2.5

1.9

Dipstick proteinuriaa

Trace

Neg

Trace

Neg

Neg

+

Previous symptoms or complication of ADPKD (yes/no)

 Cyst infection

N

N

N

N

N

N

 Urinary infection

Y

N

N

Y

N

N

 Flank pain

N

N

N

Y

Y

N

 Macrohematuria

N

N

N

Y

Y

N

 Other

N

N

N

N

N

N

Past medical history (yes/no)

 DM

N

N

N

N

N

N

 HTN

Y

Y

Y

Y

Y

Y

 ADPLD

N

N

N

N

N

Y

 Other (name)

L4, L5 laminectomy, kidney stone

Varicocelectomy

Low back pain, kidney stone

Incarcerated spinal disc, canal stenosis, kidney stone, fatty liver grade I

Hypothyroidism, kidney stone, C/S surgery

Hysterectomy

Diagnosis of HTN, age

40

32

19

22

36

44

Duration of CKD at enrollment (estimation by month)

62

132

36

14

120

120

Smoking history (yes/no)

N

N

N

N

N

N

Alcohol consumption history (yes/no)

N

N

N

N

N

N

Family history of ADPKD (yes/no)

N

Y

Y

Y

Y

Y

Under controlled diet (yes/no)b

Y

Y

Y

Y

Y

Y

Drug list (name/dose)

Metoral 50 mg/daily calcitrol I daily PD-poetin each 10 days

Gemfibrozil 300 mg/daily losartan 25 mg/daily amlodipine 5 mg/daily allopurinol 100 mg/daily calcium I daily

Enalapril 5 mg/daily losartan 25 mg/daily

Losartan 25 mg/daily atenolol 50 mg/daily diltiazem 60 mg/daily prazocin 5 mg/daily allopurinol 100 mg/daily, nephrovit I daily, vit D3 I biweekly

Losartan 25 mg ½ daily atorvastatin 20 mg/daily allopurinol 100 mg ½ daily levothyroxine ½ daily calcitrol in 5 days of week

Losartan 50 mg bid amilodipine 50 mg/daily allopurinol 100 mg/daily

  1. BMI body mass index, BP blood pressure, eGFR estimated glomerular filtration rate, DTPA diethylenetriaminepentaacetic acid, ADPKD autosomal dominant polycystic kidney disease, DM diabetes mellitus, HTN hypertension, ADPLD autosomal dominant polycystic liver disease, CKD chronic kidney disease, NA not applicable, N no, Y yes
  2. a Neg: 0 mg/dl; Trace: 15–30 mg/dl; +: 30–100 mg/dl; ++: 100–300 mg/d; +++: 300–1000 mg/dl; ++++: >1000 mg/dl
  3. b Under controlled diet is defined as: no: on normal diet; yes: patients have been under the recommendation of nutritionist by taking low protein, low salt diet, with low caffeine and high intake of water