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Table 2 Patient characteristics and demographic data at the time of enrollment

From: Safety and tolerability of autologous bone marrow mesenchymal stromal cells in ADPKD patients

Patient number 1 2 3 4 5 6
Sex (m/f) F M M M F F
Age (years) 45 37 39 28 51 54
Race Caucasian Caucasian Caucasian Caucasian Caucasian Caucasian
Educational level Graduate studies Completed high school Graduate studies Graduate studies Completed high school Completed high school
Marital status Married Married Married Married Married Married
Number of children 2 1 2 0 2 2
Employment Full-time employment Full-time employment Part-time employment Full-time employment Retired Homemaker
Diagnosis due to Incidental imaging Screening Screening Screening Screening Screening
BMI (kg/m2) 29.38 26.45 26.18 35.51 24.34 23.41
Blood group O+ A- A+ O+ B+ B+
BP sitting position (mm Hg) 135/80 115/79 110/70 131/70 133/73 127/83
eGFR (ml/min/1.73 m2) 25 32 25 25 25 29
GFR DTPA SCAN 23 41.6 24 28 26 32.83
Serum creatinine (mg/dl) 2.3 2.3 2.8 3.0 2.5 1.9
Dipstick proteinuriaa Trace Neg Trace Neg Neg +
Previous symptoms or complication of ADPKD (yes/no)
 Cyst infection N N N N N N
 Urinary infection Y N N Y N N
 Flank pain N N N Y Y N
 Macrohematuria N N N Y Y N
 Other N N N N N N
Past medical history (yes/no)
 DM N N N N N N
 HTN Y Y Y Y Y Y
 ADPLD N N N N N Y
 Other (name) L4, L5 laminectomy, kidney stone Varicocelectomy Low back pain, kidney stone Incarcerated spinal disc, canal stenosis, kidney stone, fatty liver grade I Hypothyroidism, kidney stone, C/S surgery Hysterectomy
Diagnosis of HTN, age 40 32 19 22 36 44
Duration of CKD at enrollment (estimation by month) 62 132 36 14 120 120
Smoking history (yes/no) N N N N N N
Alcohol consumption history (yes/no) N N N N N N
Family history of ADPKD (yes/no) N Y Y Y Y Y
Under controlled diet (yes/no)b Y Y Y Y Y Y
Drug list (name/dose) Metoral 50 mg/daily calcitrol I daily PD-poetin each 10 days Gemfibrozil 300 mg/daily losartan 25 mg/daily amlodipine 5 mg/daily allopurinol 100 mg/daily calcium I daily Enalapril 5 mg/daily losartan 25 mg/daily Losartan 25 mg/daily atenolol 50 mg/daily diltiazem 60 mg/daily prazocin 5 mg/daily allopurinol 100 mg/daily, nephrovit I daily, vit D3 I biweekly Losartan 25 mg ½ daily atorvastatin 20 mg/daily allopurinol 100 mg ½ daily levothyroxine ½ daily calcitrol in 5 days of week Losartan 50 mg bid amilodipine 50 mg/daily allopurinol 100 mg/daily
  1. BMI body mass index, BP blood pressure, eGFR estimated glomerular filtration rate, DTPA diethylenetriaminepentaacetic acid, ADPKD autosomal dominant polycystic kidney disease, DM diabetes mellitus, HTN hypertension, ADPLD autosomal dominant polycystic liver disease, CKD chronic kidney disease, NA not applicable, N no, Y yes
  2. Neg: 0 mg/dl; Trace: 15–30 mg/dl; +: 30–100 mg/dl; ++: 100–300 mg/d; +++: 300–1000 mg/dl; ++++: >1000 mg/dl
  3. Under controlled diet is defined as: no: on normal diet; yes: patients have been under the recommendation of nutritionist by taking low protein, low salt diet, with low caffeine and high intake of water