From: Safety and tolerability of autologous bone marrow mesenchymal stromal cells in ADPKD patients
Patient number | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|
Sex (m/f) | F | M | M | M | F | F |
Age (years) | 45 | 37 | 39 | 28 | 51 | 54 |
Race | Caucasian | Caucasian | Caucasian | Caucasian | Caucasian | Caucasian |
Educational level | Graduate studies | Completed high school | Graduate studies | Graduate studies | Completed high school | Completed high school |
Marital status | Married | Married | Married | Married | Married | Married |
Number of children | 2 | 1 | 2 | 0 | 2 | 2 |
Employment | Full-time employment | Full-time employment | Part-time employment | Full-time employment | Retired | Homemaker |
Diagnosis due to | Incidental imaging | Screening | Screening | Screening | Screening | Screening |
BMI (kg/m2) | 29.38 | 26.45 | 26.18 | 35.51 | 24.34 | 23.41 |
Blood group | O+ | A- | A+ | O+ | B+ | B+ |
BP sitting position (mm Hg) | 135/80 | 115/79 | 110/70 | 131/70 | 133/73 | 127/83 |
eGFR (ml/min/1.73Â m2) | 25 | 32 | 25 | 25 | 25 | 29 |
GFR DTPA SCAN | 23 | 41.6 | 24 | 28 | 26 | 32.83 |
Serum creatinine (mg/dl) | 2.3 | 2.3 | 2.8 | 3.0 | 2.5 | 1.9 |
Dipstick proteinuriaa | Trace | Neg | Trace | Neg | Neg | + |
Previous symptoms or complication of ADPKD (yes/no) | ||||||
 Cyst infection | N | N | N | N | N | N |
 Urinary infection | Y | N | N | Y | N | N |
 Flank pain | N | N | N | Y | Y | N |
 Macrohematuria | N | N | N | Y | Y | N |
 Other | N | N | N | N | N | N |
Past medical history (yes/no) | ||||||
 DM | N | N | N | N | N | N |
 HTN | Y | Y | Y | Y | Y | Y |
 ADPLD | N | N | N | N | N | Y |
 Other (name) | L4, L5 laminectomy, kidney stone | Varicocelectomy | Low back pain, kidney stone | Incarcerated spinal disc, canal stenosis, kidney stone, fatty liver grade I | Hypothyroidism, kidney stone, C/S surgery | Hysterectomy |
Diagnosis of HTN, age | 40 | 32 | 19 | 22 | 36 | 44 |
Duration of CKD at enrollment (estimation by month) | 62 | 132 | 36 | 14 | 120 | 120 |
Smoking history (yes/no) | N | N | N | N | N | N |
Alcohol consumption history (yes/no) | N | N | N | N | N | N |
Family history of ADPKD (yes/no) | N | Y | Y | Y | Y | Y |
Under controlled diet (yes/no)b | Y | Y | Y | Y | Y | Y |
Drug list (name/dose) | Metoral 50 mg/daily calcitrol I daily PD-poetin each 10 days | Gemfibrozil 300 mg/daily losartan 25 mg/daily amlodipine 5 mg/daily allopurinol 100 mg/daily calcium I daily | Enalapril 5 mg/daily losartan 25 mg/daily | Losartan 25 mg/daily atenolol 50 mg/daily diltiazem 60 mg/daily prazocin 5 mg/daily allopurinol 100 mg/daily, nephrovit I daily, vit D3 I biweekly | Losartan 25 mg ½ daily atorvastatin 20 mg/daily allopurinol 100 mg ½ daily levothyroxine ½ daily calcitrol in 5 days of week | Losartan 50 mg bid amilodipine 50 mg/daily allopurinol 100 mg/daily |