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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos

Fig. 5

Copy number variants of unknown clinical significance. Data for individual microarray probes are represented by dots and plotted on a log2 scale of the ratio of hESC DNA/reference DNA. Sub-images are not to scale. Aberrations detected by Cytosure™ Interpret software are visible as shaded segments and the average log2 ratio of these segments is indicated by thick solid lines. a Approximately 3.1–3.2 Mb loss of 10q21.1 seen in MAN10 (b) approximately 87–94 kb gain of Xp22.33 seen in MAN11 (c) approximately 94–189 kb gain of Xp11.21 seen in MAN13 (d) gain of 20q11.21 seen in MAN13 (blue data approximately 1.1–1.4 Mb ) and MAN14 (green data approximately 1.01–1.1 Mb) (e) approximately 187–277 kb loss of 2p15 seen in MAN15 (f) approximately 346–465 kb gain of 6q26 seen in MAN15

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