Fig. 8From: Human adult mesangiogenic progenitor cells reveal an early angiogenic potential, which is lost after mesengenic differentiationHistological examination of chicken embryo CAM grafts. Application of “no cell” grafts did not alter CAM morphology, allowing clear identification of the three-layer structure formed by endoderm (ED), mesoderm (M), and ectoderm (ET). MPC grafts showed extended areas of Geltrex™ degradation and intense tissue remodeling, with an increased number of newly formed microvessels (arrows, exploded frame). P2-MSC implants maintained their compact structure and did not interact with CAM; no increment of vascularization was detected. HUVEC grafts revealed Geltrex™ degradation, CAM remodeling, and increased vascularization. Two representative samples for each cell type are displayed. HUVEC human umbilical vein endothelial cell, MPC mesangiogenic progenitor cell, MSC mesenchymal stromal cellBack to article page