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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells

Fig. 2

Migration assay. AMSCs in EBM, EGM, EGM + MMP-2 siRNA, EGM + MMP-14 siRNA, and EGM + ATR2 siRNA showed migration activity after 24 hours of making the scratches (a). MMP-2 and MMP-14 siRNA resulted in significant decrease in the number of migrated cells per field compared with EGM-only cells, whereas ATR2 siRNA silencing had no effect on the migration activity of AMSCs during EC differentiation (b). **p < 0.01. EBM endothelial cell basal medium, EGM endothelial cell growth medium, MMP matrix metalloproteinase, ATR2 angiotensin receptor R2

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Stem Cell Research & Therapy

ISSN: 1757-6512