Fig. 6From: ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cellsDose-dependent inhibition of ERK by VEGFR2 kinase inhibitor. Western blot analysis of p-ERK with three different concentration of VEGFR2 kinase inhibitor (0.1, 2.0, and 5.0 μM), showed significant decrease in ERK phosphorylation with 5.0 μM of VEGFR2 kinase inhibitor. Phospho-ERK was normalized to its total protein expression. *p < 0.05. EBM endothelial cell basal medium, EGM endothelial cell growth medium, ERK extracellular signal-regulated kinase, VEGFR2 vascular endothelial growth factor receptor-2Back to article page