TY - JOUR AU - Kohno, Yuji AU - Mizuno, Mitsuru AU - Ozeki, Nobutake AU - Katano, Hisako AU - Komori, Keiichiro AU - Fujii, Shizuka AU - Otabe, Koji AU - Horie, Masafumi AU - Koga, Hideyuki AU - Tsuji, Kunikazu AU - Matsumoto, Mikio AU - Kaneko, Haruka AU - Takazawa, Yuji AU - Muneta, Takeshi AU - Sekiya, Ichiro PY - 2017 DA - 2017/05/16 TI - Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients JO - Stem Cell Research & Therapy SP - 115 VL - 8 IS - 1 AB - Mesenchymal stem cells derived from the synovial membrane (synovial MSCs) are a candidate cell source for regenerative medicine of cartilage and menisci due to their high chondrogenic ability. Regenerative medicine can be expected for RA patients with the inflammation well-controlled as well as OA patients and transplantation of synovial MSCs would also be a possible therapeutic treatment. Some properties of synovial MSCs vary dependent on the diseases patients have, and whether or not the pathological condition of RA affects the chondrogenesis of synovial MSCs remains controversial. The purpose of this study was to compare the properties of primary synovial MSCs between RA and OA patients. SN - 1757-6512 UR - https://doi.org/10.1186/s13287-017-0572-8 DO - 10.1186/s13287-017-0572-8 ID - Kohno2017 ER -