Table 2 Summary of previous and current reports for comparison of synovial MSCs between RA and OA patients
Author | Jones [15] | Skalska [17] | Koizumi [18] | Kohno |
|---|---|---|---|---|
Sample number | RA (n = 45) OA (n = 11) | RA (n = 24) OA (n = 18) | RA (n = 13) OA (n = 6) | RA (n = 8) OA (n = 8) |
RA synovium collection method | Biopsy with arthroscopy | TKA | TKA, arthroplasty for forefoot, synovectomy for hand | TKA |
Passage number for analysis | Passage 3 | Passage 4 | Passage 2–4 | Passage 0 |
Comparison between RA and OA | Surface epitopes: similar | Surface epitopes: similar | Gene expression: similar | Nucleated cell number: similar |
Chondro: RA < OA | Chondro: similar | In vitro and in vivo | Yields: similar | |
Chondro: similar | Surface epitopes: similar | |||
Chondro: similar | ||||
CRP | 0–15(mg/dl) | 0.5–8 (mg/dl) | 0–0.3 (mg/dl) | 0–6 (mg/dl) |