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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: The combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects

Fig. 3

Bone mineral density analysis. a Images of calvarial bone obtained using LUNAR PIXImus system, 8 weeks after surgery. General X-ray view (lower row) and X-ray with color outlined bone regeneration images (upper row) are showed. The black area circled with green line indicates low density area (fibrous tissue). The gray area between the green line and the yellow lines is the newly-formed bone area. b Quantitative analysis of bone density from A (n = 3). c ALP activity of newly formed bone (n = 3). * p < 0.05; ** p < 0.01; *** p < 0.001; ns: not statistically significant. ALP alkaline phosphatase, B2 bone morphogenetic protein 2, MSCs mesenchymal stem cells, nCS nano-calcium sulfate, PRP platelet-rich plasma

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Stem Cell Research & Therapy

ISSN: 1757-6512