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Table 3 Major applications of SVF- and ADSC-based therapeutics with corresponding clinical trials and/or case study references

From: Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

 

Indications

Clinical trials (www.ClinicalTrials.gov)

Case studies and other references

Cosmetic applications

Breast augmentation

NCT02116933

[14, 16, 30, 65, 68, 69]

General scar, burn and wounds, facial rejuvenation, reconstruction

None found

[10, 23, 65, 70, 71]

Androgenic alopecia

NCT02594046

None found

Disease conditions

Vulvar lichen sclerosus

None found

[31]

Erectile dysfunction

NCT02414308, NCT01601353, NCT02087397

[67]

Peyronie’s disease

NCT02414308

None found

Urinary incontinence

NCT01799694, NCT01850342

None found

Faecal incontinence

NCT02292628, NCT01011686

None found

Anal fistula

None found

[72]

Multiple Sclerosis

None found

[73]

Critical limb ischaemia

None found

[74, 75]

Diabetic foot ulcer

NCT02394886, NCT02092870

None found

Osteoarthritis

NCT02326961 (Using Celution system)

[76]

  1. This Table provides an overview of major ailments in which ADSCs and SVF are being used therapeutically, with references of case studies and listed clinical trials within www.ClinicalTrials.gov [10, 14, 16, 23, 30, 31, 65,66,67,68,69,70,71,72,73,74,75,76]
  2. For certain indications, either ClinicalTrial.gov or published cases were not found while preparing this manuscript; this may change in the future
  3. ADSC adipose-derived stem/stromal cell, SVF stromal vascular fraction