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Table 3 Major applications of SVF- and ADSC-based therapeutics with corresponding clinical trials and/or case study references

From: Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

  Indications Clinical trials (www.ClinicalTrials.gov) Case studies and other references
Cosmetic applications Breast augmentation NCT02116933 [14, 16, 30, 65, 68, 69]
General scar, burn and wounds, facial rejuvenation, reconstruction None found [10, 23, 65, 70, 71]
Androgenic alopecia NCT02594046 None found
Disease conditions Vulvar lichen sclerosus None found [31]
Erectile dysfunction NCT02414308, NCT01601353, NCT02087397 [67]
Peyronie’s disease NCT02414308 None found
Urinary incontinence NCT01799694, NCT01850342 None found
Faecal incontinence NCT02292628, NCT01011686 None found
Anal fistula None found [72]
Multiple Sclerosis None found [73]
Critical limb ischaemia None found [74, 75]
Diabetic foot ulcer NCT02394886, NCT02092870 None found
Osteoarthritis NCT02326961 (Using Celution system) [76]
  1. This Table provides an overview of major ailments in which ADSCs and SVF are being used therapeutically, with references of case studies and listed clinical trials within www.ClinicalTrials.gov [10, 14, 16, 23, 30, 31, 65,66,67,68,69,70,71,72,73,74,75,76]
  2. For certain indications, either ClinicalTrial.gov or published cases were not found while preparing this manuscript; this may change in the future
  3. ADSC adipose-derived stem/stromal cell, SVF stromal vascular fraction