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Table 4 Comparative overview of SVF and ADSCs

From: Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

Factors

SVF

ADSCs

Cell population

Heterogeneous

Homogeneous

Cell type

ADSC, EC, EPC, etc.

ADSC only

Application range

Autologous

Autologous & allogeneic

Immune rejection

Not anticipated

Immune monitoring required

Properties

Angiogenic, immunomodulatory, and differentiative

Immunomodulatory and differentiative

Ex vivo exposure

Low (hours)

High (weeks)

Documented advantage in application

Acute myocardial infarction [9] Chronic experimental autoimmune encephalomyelitis [11] Erectile dysfunction in rat model of cavernous nerve injury [12]

Hypertrophic scars [77]

  1. This table provides a comparative overview of ADSCs and SVF with respect to various criteria and lists a few studies which observe advantage of one over the other [9, 11, 12, 77]
  2. ADSC adipose-derived stem/stromal cell, EC endothelial cell, EPC endothelial precursor cell, SVF stromal vascular fraction