Factors | SVF | ADSCs |
---|---|---|
Cell population | Heterogeneous | Homogeneous |
Cell type | ADSC, EC, EPC, etc. | ADSC only |
Application range | Autologous | Autologous & allogeneic |
Immune rejection | Not anticipated | Immune monitoring required |
Properties | Angiogenic, immunomodulatory, and differentiative | Immunomodulatory and differentiative |
Ex vivo exposure | Low (hours) | High (weeks) |
Documented advantage in application | Acute myocardial infarction [9] Chronic experimental autoimmune encephalomyelitis [11] Erectile dysfunction in rat model of cavernous nerve injury [12] | Hypertrophic scars [77] |