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Table 4 Comparative overview of SVF and ADSCs

From: Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation

Factors SVF ADSCs
Cell population Heterogeneous Homogeneous
Cell type ADSC, EC, EPC, etc. ADSC only
Application range Autologous Autologous & allogeneic
Immune rejection Not anticipated Immune monitoring required
Properties Angiogenic, immunomodulatory, and differentiative Immunomodulatory and differentiative
Ex vivo exposure Low (hours) High (weeks)
Documented advantage in application Acute myocardial infarction [9] Chronic experimental autoimmune encephalomyelitis [11] Erectile dysfunction in rat model of cavernous nerve injury [12] Hypertrophic scars [77]
  1. This table provides a comparative overview of ADSCs and SVF with respect to various criteria and lists a few studies which observe advantage of one over the other [9, 11, 12, 77]
  2. ADSC adipose-derived stem/stromal cell, EC endothelial cell, EPC endothelial precursor cell, SVF stromal vascular fraction