Fig. 5

Downregulation of miR-223 in MSCs decreased cell viability and accelerated the apoptosis process in RTECs. All RTECs were treated with hypoxia/reoxygenation stimulation. The MSCs had been pretreated with a miR-223 inhibitor. The RTECs and MSCs were then cocultured in a double-chamber. a RTEC viability was measured with the CCK-8 assay. b Representative images of apoptotic RTECs at 48 h as detected by flow cytometry, *P < 0.05, n = 3. NC negative control, OD optical density, PI propidium iodide