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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma

Fig. 2

Experimental design. C57BL/6 female mice were divided into two groups: CTRL (sensitized and challenged with saline) and OVA (sensitized and challenged with ovalbumin). Seven intraperitoneal (i.p.) sensitizations were performed. On days 40, 43, and 46 after first sensitization, an intratracheal challenge (i.t.) was performed. Treatment was administered intravenously (i.v.); 1 day after the last challenge and 7 days after this treatment, the animals were euthanized for data acquisition. The treatment consisted of saline (SAL), human adipose-derived mesenchymal stromal cells (AD-MSC), or extracellular vesicles (EV) at a dose equivalent to 105 AD-MSC (37 μg of total protein)

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Stem Cell Research & Therapy

ISSN: 1757-6512