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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Global gene expression profiling and senescence biomarker analysis of hESC exposed to H2O2 induced non-cytotoxic oxidative stress

Fig. 1

Global transcriptome analysis of hESCs, HUES3, treated with different concentrations of H2O2. Heatmap visualization of upregulated (a) and downregulated (c) genes following 4, 8 and 16 μM H2O2 treatments. Replicates are displayed in the vertical axis, genes on horizontal axis. Log2-transformed signal intensities are depicted in colour code. Venn diagram of the upregulated (b) and downregulated (d) genes that are significantly different between control and H2O2 treated HUES3 cells. Of the 569 genes significantly upregulated between control and treated HUES3 cells 17 genes showed significant change by stage in all three H2O2 treatments (4, 8 and 16 μM). And of the 485 genes significantly downregulated between control (CTR) and treated HUES3 cells eight genes showed significant change by stage in all three H2O2 treatments

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