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Table 1 Baseline animal parameters and perfusate composition

From: Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model

  CONTR MAPC p value
Baseline animal
 Weight (kg) 40.3 (38.8–41.2) 42.3 (40.2–43.1) 0.10
 Vt (mL/kg) 7.9 (7.8–8.0) 7.9 (7.8–7.9) 0.85
 HR (bpm) 88 (73–118) 107 (94–148) 0.17
 MAP (mmHg) 102 (90–113) 96 (77–106) 0.42
 Peak Awp (cmH2O) 19.5 (18.8–21.3) 18.5 (17.5–19.3) 0.16
 PaO2/FiO2 (mmHg) 413 (399–455) 405 (376–421) 0.37
 WBC (109/L) 19.8 (14.3–24.7) 18.5 (15.2–21.2) 0.62
 Neutrophils (%) 42.5 (32.3–51.0) 46.0 (37.5–52.5) 0.68
Perfusate composition
 Albumin (g/L) 65.5 (64.0–66.9) 66.8 (63.5–68.8) 0.47
 Osmolality (mmol/kg H2O) 318 (614–320) 318 (315–319) 0.85
 Na (mmol/L) 154 (154–156) 155 (153–156) 0.79
 K (mmol/L) 3.5 (3.5–3.6) 3.5 (3.5–3.6) 0.51
 CI (mmol/L) 105 (104–106) 105 (104–105) 0.29
 Bicarbonate (mmol/L) 31.2 (29.6–31.9) 32.6 (30.6–33.1) 0.16
 Ca (mmol/L) 0.57 (0.55–0.57) 0.53 (0.52–0.56) 0.10
 Glucose (mg/dL) 233 (230–239) 236 (229–248) 0.98
  1. Comparable animal weight and baseline hemodynamic parameters. No signs of systemic inflammation (normal WBC count, normal neutrophil count, normal temperature). Perfusate composition is similar between both groups for albumin, osmolality, glucose, and electrolytes.
  2. CONTR control group, MAPC multipotent adult progenitor cell, Vt tidal volume, HR heart rate, MAP mean arterial pressure, Peak AwP peak airway pressure, PaO 2 /FiO2 partial oxygen pressure/fractional inspired oxygen concentration, WBC white blood cell count, Na sodium, K potassium, Cl chloride, Ca calcium