Umbilical cord-derived mesenchymal stromal cells: predictive obstetric factors for cell proliferation and chondrogenic differentiation

Table 1 Influence of obstetric factors on Wharton’s jelly-derived mesenchymal stromal cell (WJ-MSC) properties

Obstetric factors	WJ-MSC properties	References
Maternal age	Negative correlation with mesenchymal markers (CD105/CD29) expression	Alrefaei et al. [17]
Gestational diabetes	Improved adipogenic differentiation	Pierdomenico et al. [18]
Gestational diabetes	Decreased proliferation capacity and viability	Wajid et al. [19]
Obese mothers	Improved adipogenic differentiation	Boyle et al. [20]
Preeclampsia	Improved neuroglial differentiation	Joerger-Messerli et al. [21]
Preterm birth	Similar neuroglial differentiation potential as full-term birth	Messerli et al. [22]
Full-term birth	Enhanced osteoblastic potential	Penolazzi et al. [23]

ISSN: 1757-6512