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Table 1 Influence of obstetric factors on Wharton’s jelly-derived mesenchymal stromal cell (WJ-MSC) properties

From: Umbilical cord-derived mesenchymal stromal cells: predictive obstetric factors for cell proliferation and chondrogenic differentiation

Obstetric factors WJ-MSC properties References
Maternal age Negative correlation with mesenchymal markers (CD105/CD29) expression Alrefaei et al. [17]
Gestational diabetes Improved adipogenic differentiation Pierdomenico et al. [18]
Decreased proliferation capacity and viability Wajid et al. [19]
Obese mothers Improved adipogenic differentiation Boyle et al. [20]
Preeclampsia Improved neuroglial differentiation Joerger-Messerli et al. [21]
Preterm birth Similar neuroglial differentiation potential as full-term birth Messerli et al. [22]
Full-term birth Enhanced osteoblastic potential Penolazzi et al. [23]