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Fig. 11 | Stem Cell Research & Therapy

Fig. 11

From: RETRACTED ARTICLE: Ang II-AT2R increases mesenchymal stem cell migration by signaling through the FAK and RhoA/Cdc42 pathways in vitro

Fig. 11

Schematic of Ang II-AT2R-increased MSC migration by signaling through the FAK and RhoA/Cdc42 pathways. Ang II-AT2R activates FAK, leading to the formation of focal contacts and organization of the cytoskeleton, which is mediated by RhoA and Cdc42, and increases the migration of MSCs. Ang II angiotensin II, AT1R angiotensin II type 1 receptor, AT2R angiotensin II type 2 receptor, FAK focal adhesion kinase

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