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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Interleukin-3 enhances the migration of human mesenchymal stem cells by regulating expression of CXCR4

Fig. 3

Effect of IL-3 on expression of chemokine receptors and integrins involved in migration of MSCs. BM-MSCs, AT-MSCs and GT-MSCs were treated with IL-3 (100 ng/ml) for 24 hours and surface expression of different chemokine receptors and integrins was analyzed by flow cytometry. ac Fold change as percentage of cells expressing chemokine receptors and integrins. d Fold change in percentage of cells expressing intracellular CXCR4 analyzed after IL-3 treatment in permeabilized MSCs. Data shown as mean ± SEM of three independent experiments. *p ≤ 0.05 and **p ≤ 0.01 vs control groups. AT adipose tissue, BM bone marrow, CTRL control, GT gingival tissue, IL-3 interleukin-3, MSC mesenchymal stem cell

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