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Table 1 Baseline characteristics (n = 50)

From: Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia

Parameter

Baseline

Age (years)

64 ± 11

Male:female (n)

44:6

Diabetes mellitus

30 (60%)

Arterial hypertension

38 (76%)

Hyperlipidemia

27 (54%)

BMI (kg/m2)

28 ± 4

LVEF (%)

55 ± 7

Smoking

21 (42%)

Rutherford category

5.1 ± 0.3

Creatinine (μmol/L)

95 ± 51

CRP (mg/L)

22 ± 37

Leukocytes (109/L)

9.1 ± 4.9

BM-MNCs in BMC (109 cells)

4.2 ± 1.5

CD34+ in BMC (106 cells)

28.1 ± 14.7

VEGF (pg/mL)

173 ± 191

Cholesterol (mmol/L)

4.3 ± 1.1

TAG (mmol/L)

1.4 ± 1.1

LDL (mmol/L)

2.8 ± 1.4

oxLDL (U/L)

24.3 ± 7.7

HDL (mmol/L)

1.2 ± 0.4

Atorvastatin (mg/day)

16 ± 11

  1. BMC bone marrow concentrate, BMI body mass index, BM-MNC bone marrow-derived mononuclear cell, CRP C-reactive protein, HDL high-density lipoprotein, LDL low-density lipoprotein, LVEF left ventricle ejection fraction, oxLDL oxidized low-density lipoprotein, TAG triglycerides, VEGF vascular endothelial growth factor