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Table 2 Functional limb ischemia outcomes in patients with limb salvage after BM-MNC application (n = 37)

From: Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia

 

Baseline

6-month follow-up

p (baseline vs 6-month follow-up)

All patients (n = 37)

IM (n = 18)

IA (n = 19)

All patients (n = 37)

IM (n = 18)

IA (n = 19)

All patients

IM

IA

tcpO2 (mmHg)

16 ± 10

16 ± 10

17 ± 10

29 ± 14

30 ± 16

28 ± 12

<0.001

<0.001

<0.005

ABI

0.8 ± 0.3

0.8 ± 0.3

0.8 ± 0.3

0.9 ± 0.3

0.9 ± 0.2

0.9 ± 0.3

0.1

0.06

0.36

Pain scale (0–10)

4.4 ± 2.4

3.8 ± 2.1

5.0 ± 2.5

1.6 ± 1.6

1.2 ± 1.0

1.9 ± 1.9

<0.001

<0.001

<0.001

Rutherford category

5.0

5.0

5.0

4.0 ± 1.3

3.8 ± 1.3

4.2 ± 1.1

<0.001

<0.001

<0.005

  1. ABI ankle-brachial index, BM-MNC bone marrow-derived mononuclear cell, IA intra-arterial, IM intramuscular, tcpO 2 transcutaneous oxygen pressure