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Table 2 Functional limb ischemia outcomes in patients with limb salvage after BM-MNC application (n = 37)

From: Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia

  Baseline 6-month follow-up p (baseline vs 6-month follow-up)
All patients (n = 37) IM (n = 18) IA (n = 19) All patients (n = 37) IM (n = 18) IA (n = 19) All patients IM IA
tcpO2 (mmHg) 16 ± 10 16 ± 10 17 ± 10 29 ± 14 30 ± 16 28 ± 12 <0.001 <0.001 <0.005
ABI 0.8 ± 0.3 0.8 ± 0.3 0.8 ± 0.3 0.9 ± 0.3 0.9 ± 0.2 0.9 ± 0.3 0.1 0.06 0.36
Pain scale (0–10) 4.4 ± 2.4 3.8 ± 2.1 5.0 ± 2.5 1.6 ± 1.6 1.2 ± 1.0 1.9 ± 1.9 <0.001 <0.001 <0.001
Rutherford category 5.0 5.0 5.0 4.0 ± 1.3 3.8 ± 1.3 4.2 ± 1.1 <0.001 <0.001 <0.005
  1. ABI ankle-brachial index, BM-MNC bone marrow-derived mononuclear cell, IA intra-arterial, IM intramuscular, tcpO 2 transcutaneous oxygen pressure