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Table 3 Decrease in ADMA, TNF-α, and inflammatory and related parameters in patients with limb salvage after BM-MNC application (n = 37)

From: Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia

  Baseline 6-month follow-up p
ADMA (μmol/L) 1.74 ± 0.66 0.90 ± 0.49 <0.001
TNFα (pg/mL) 2.22 ± 0.16 1.94 ± 0.38 <0.001
Homocysteine (μmol/L) 12.2 ± 3.5 12.0 ± 3.1 0.29
CRP (mg/L) 14.3 ± 23.9 8.4 ± 13.7 0.15
IL-6 (pg/ml) 1.74 ± 0.9 1.76 ± 0.7 0.49
Leukocytes (109/L) 8.6 ± 5.2 7.9 ± 2.3 0.20
Creatinine (μmol/L) 90 ± 38 89 ± 39 0.48
  1. ADMA asymmetric dimethylarginine, BM-MNC bone marrow-derived mononuclear cell, CRP C-reactive protein, IL interleukin, TNF tumor necrosis factor