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Table 4 Markers of oxidative stress in patients with limb salvage after BM-MNC application (n = 37)
| Parameter of oxidative stress | Baseline | 3-month follow-up | 6-month follow-up | p* |
|---|---|---|---|---|
| Markers of endogenous antioxidant capacity | ||||
| SOD (U/L) | 168 ± 50 | 178 ± 48 | 218 ± 37 | 0.002 |
| GSH (μmol/L) | 7.0 ± 3.1 | 8.8 ± 6.3 | 8.7 ± 4.2 | 0.02 |
| Apo(a) (g/L) | 0.26 ± 0.16 | 0.28 ± 0.17 | 0.33 ± 0.19 | 0.03 |
| Retinol (μmol/L) | 2.6 ± 0.9 | 2.4 ± 0.66 | 2.3 ± 0.7 | 0.01 |
| Coenzyme Q10 (μg/L) | 468 ± 182 | 594 ± 248 | 598 ± 283 | 0.02 |
| Vitamin C (μmol/L) | 22 ± 15 | 26 ± 16 | 29 ± 20 | 0.09 |
| Vitamin C/Vitamin E | 1.2 ± 0.9 | 1.4 ± 1 | 1.7 ± 1.4 | 0.07 |
| FRAP (μmol/L) | 951 ± 645 | 866 ± 235 | 845 ± 170 | 0.1 |
| TAS (U/ml) | 1.5 ± 0.3 | 1.5 ± 0.2 | 1.5 ± 0.2 | 0.2 |
| Oxystat (μmol/L) | 775 ± 563 | 885 ± 720 | 959 ± 796 | 0.1 |
| Markers of oxidative stress damage | ||||
| PC (μmol/L) | 131 ± 32 | 117 ± 30 | 106 ± 19 | 0.004 |
| MDA (μmol/L) | 1.1 ± 0.5 | 1.0 ± 0.6 | 1.1 ± 0.6 | 0.39 |
| oxLDL (U/L) | 23.4 ± 7.7 | 28.2 ± 17 | 25.9 ± 8.0 | 0.1 |
| DNA fragmentation (AU) | 59 ± 32 | 54 ± 22 | 54 ± 19 | 0.24 |
