Fig. 8
In-vivo antimicrobial efficacy of antimicrobial-loaded hydrogels in SA-inoculated wounds with histological analysis. a Wound bed images of SA-inoculated full-thickness cutaneous wounds (ticks millimeter marks) before hydrogel treatment and 3 days after hydrogel treatment. b SA colony forming abilities after 1 and 3 days in the wound bed with hydrogels. c. H&E representative full-thickness wound images of one side of the wound (100× magnification, scale bar 2 μm, E epithelial layer). d Epidermal thickness in wounds 3 days after hydrogel treatment. *p < 0.05, ****p < 0.001. CFU colony forming unit, MSC mesenchymal stromal/stem cell, MSCs + mino. + vanco. + lin. 1 × 106 MSCs/ml + 50 μg/ml minocycline + 40 μg/ml vancomycin + 10 μg/ml linezolid