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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation

Fig. 2

Effects of small-molecule combinations on marker purity and cellular fold expansion. a CD34 expression and CD34+ cellular fold expansion for different combinations of small molecules. b,c VPA and C433 concentration adjustment. PB CD34+ cells were cultured with the three core cytokines, 1 μM stemregenin1 (SR1), and various concentrations of valproic acid (VPA) (b) or CAY10433 (C433) (c). d Final optimization of the compound combination. Data are shown as mean ± SD, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001. NC negative control, VC vehicle control

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