Groups | Medium content | CD34 (%) |
---|
Small molecules | Cytokines |
---|
SMC | SR1 + VPA | TSF | 90.5 ± 0.5*#†‡
|
SR1 + C433 |  | 86.6 ± 12.5*#§
|
SR1 + VPA + C433 |  | 94.5 ± 4.3*#
|
VC | DMSO | TSF | 56.6 ± 1.8 |
39.8 ± 0.7 |
52.2 ± 1.7 |
SMCO | SR1 + VPA | Absent | N/A |
SR1 + C433 |
SR1 + VPA + C433 |
NC | Absent | TSF | 45.5 ± 0.2 |
BC | Absent | Absent | N/A |
- The cells were not enough for the flow cytometry detection of the SMCO group
- Data are shown as mean ± SD (n = 3)
- *p < 0.01, SMC vs VC; #
p < 0.01, SMC vs NC; â€
p < 0.01, SR1 + VPA vs SR1 + C433; ‡
p < 0.05, SR1 + VPA vs SR1 + VPA + C433; §
p < 0.05, SR1 + C433 vs SR1 + VPA + C433
-
BC basal control, C433 CAY10433, DMSO dimethyl sulfoxide, N/A not applicable, NC negative control, SMC small-molecule combination, SMCO small-molecule combination only, SR1 stemregenin1, TSF TPO + SCF + Flt3-L, VC vehicle control, VPA valproic acid