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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix

Fig. 2

Recovery of cartilage destruction by intra-articular injection of ESC-MSCs in a DMM model. a Flowchart of the in vivo experiment. b The Safranin O and Fast Green staining of cartilage destruction at 8 weeks after surgery. Boxed regions were magnified and shown in the next line. Scale bars, 200 μm. c OARSI scores of cartilage destruction. n = 10 in each group. d Immunohistochemical staining of COL II and ADAMTS5. Boxed regions show the gross view. Scale bars, 100 μm. COL II collagen type II, ESC-MSCs embryonic stem cell-derived mesenchymal stem cells, OARSI Osteoarthritis Research Society International

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