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Table 1 Body and lung weights and lung:body weight ratios in 14-day-old rats exposed to RA or hyperoxia and treated with NS, MSCs, surfactant, or MSCs + surfactant on postnatal day 5

From: Surfactant effects on the viability and function of human mesenchymal stem cells: in vitro and in vivo assessment

Treatment n Body weight (g) Lung weight (g) Lung:body weight (%)
RA + NS 6 22.23 ± 2.21 0.33 ± 0.02 1.48 ± 0.17
RA + MSCs 10 22.33 ± 2.01 0.34 ± 0.02 1.48 ± 0.11
RA + surfactant 8 23.47 ± 1.28 0.35 ± 0.03 1.50 ± 0.09
RA + surfactant + MSCs 7 23.38 ± 1.48 0.35 ± 0.03 1.50 ± 0.08
O2 + NS 3 16.42 ± 3.79** 0.28 ± 0.08 1.66 ± 0.23
O2 + MSCs 4 16.38 ± 3.89** 0.27 ± 0.09 1.62 ± 0.13
O2 + surfactant 4 16.48 ± 2.64** 0.26 ± 0.05 1.57 ± 0.13
O2 + surfactant + MSCs 5 15.13 ± 5.13** 0.24 ± 0.08** 1.56 ± 0.18
  1. Values are presented as mean ± standard deviation
  2. MSCs mesenchymal stem cells, NS normal saline, O 2 oxygen-enriched atmosphere, RA room air
  3. **P < 0.01 vs. RA + MSCs, RA + surfactant, and RA + surfactant + MSCs