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Table 1 Body and lung weights and lung:body weight ratios in 14-day-old rats exposed to RA or hyperoxia and treated with NS, MSCs, surfactant, or MSCs + surfactant on postnatal day 5

From: Surfactant effects on the viability and function of human mesenchymal stem cells: in vitro and in vivo assessment

Treatment

n

Body weight (g)

Lung weight (g)

Lung:body weight (%)

RA + NS

6

22.23 ± 2.21

0.33 ± 0.02

1.48 ± 0.17

RA + MSCs

10

22.33 ± 2.01

0.34 ± 0.02

1.48 ± 0.11

RA + surfactant

8

23.47 ± 1.28

0.35 ± 0.03

1.50 ± 0.09

RA + surfactant + MSCs

7

23.38 ± 1.48

0.35 ± 0.03

1.50 ± 0.08

O2 + NS

3

16.42 ± 3.79**

0.28 ± 0.08

1.66 ± 0.23

O2 + MSCs

4

16.38 ± 3.89**

0.27 ± 0.09

1.62 ± 0.13

O2 + surfactant

4

16.48 ± 2.64**

0.26 ± 0.05

1.57 ± 0.13

O2 + surfactant + MSCs

5

15.13 ± 5.13**

0.24 ± 0.08**

1.56 ± 0.18

  1. Values are presented as mean ± standard deviation
  2. MSCs mesenchymal stem cells, NS normal saline, O 2 oxygen-enriched atmosphere, RA room air
  3. **P < 0.01 vs. RA + MSCs, RA + surfactant, and RA + surfactant + MSCs
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Stem Cell Research & Therapy

ISSN: 1757-6512