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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis

Fig. 1

Apoptosis of MSCs and expression of miR-21, PTEN, and PDCD4. a Mesenchymal stem cells (MSCs) of the third generation (×100). b MSCs transfected with LV-miR-21 at a MOI of 20, emitting green fluorescence under the fluorescence microscope (×100). c Expression of miR-21 in MSCs transfected with LV-miR-21. *P < 0.05, compared to the MSC group and the LV group. d Comparison of apoptotic rates between the groups. *P < 0.05, compared to the MSC group and the LV group. e Comparison of mRNA expression of PTEN and PDCD4 between the groups. *P < 0.05, compared to the MSC group and the LV group. f Comparison of protein expression of PTEN and PDCD4. *P < 0.05, compared to the MSC group and the LV group

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