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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Engineering human ventricular heart muscles based on a highly efficient system for purification of human pluripotent stem cell-derived ventricular cardiomyocytes

Fig. 8

Electrophysiology analysis of human ventricular heart muscles. ad Ventricular heart muscles exhibited normal electrophysiology and responded to cardiac pharmaceutical reagents. MEA recording of the field potentials and contraction rate of the engineered human heart muscles before (baseline) and after treatment of verapamil (a), nifedipine (b), E4031 (c), and epinephrine and metoprolol (d). Data shown as the mean ± SEM of three independent experiments. *P < 0.05 compared with baseline; *##P < 0.05 compared with epinephrine alone by two-tailed Student’s t test

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