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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry

Fig. 6

HBV gene modulation in infected D-UCMSCs. Gene expression analysis between HBV infected and non-infected cells shows that sodium taurocholate cotransporting peptide (NTCP) expression was not significantly modulated by HBV (p = not significant by multiple t test; n = 3). In contrast, HBV infection significantly decreases CYP3A4 expression (462.6 ± 47.4 SEM; p = 0.0008) and increases CYP7A1 expression (2.2 ± 0.081 SEM; p = 0.005). Values are expressed as relative quantity compared to UCMSCs that were not infected

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