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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks

Fig. 2

Small molecules and microRNAs improve the conversion efficiency and enable generation of iCtx from adult human skin fibroblasts. a Conversion efficiency of iCtx cells generated from HEFL cells with and without small molecule (SM) treatment (n = 3) (left). MAP2-positive cells generated by BMF along with small molecules and microRNAs (right). b MAP2-positive cells generated by BMF and small molecules from adult human skin fibroblast. Scale bar = 20 μm

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