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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells

Fig. 3

Inhibition of dendritic cell differentiation by dental MSCs. Monocytes were differentiated towards dendritic cells with rhGM-CSF and rhIL-4 alone (Mo) or in the presence of control green fluorescent protein (GFP)-mesenchymal stem cells (MSCs; light grey) and hypoxia-inducible factor (HIF)-MSCs (dark grey). After 7 days, cells were harvested, and the expression of CD14 and CD1a was analyzed by flow cytometry. A representative experiment (a) and mean ± SD of four independent experiments (b) are shown. MSCs were excluded from the analysis by CD90 expression. One-way ANOVA, *p ≤ 0.05, GFP-MSCs and HIF-MSCs versus no MSCs

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