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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Local application of IGFBP5 protein enhanced periodontal tissue regeneration via increasing the migration, cell proliferation and osteo/dentinogenic differentiation of mesenchymal stem cells in an inflammatory niche

Fig. 2

rhIGFBP5 enhanced the functions of PDLSCs in the inflammatory condition. TNFα (10 ng/ml) was used to treat PDLSCs. a-d The scratch-simulated wound migration assay results. Scale bar: 100 μm. e, f The Transwell chemotaxis assay results. Scale bar: 50 μm. g ALP activity. h Alizarin red staining. i Cell Counting Kit-8 assay results. One-way ANOVA was utilized for analysis in a-b. Student’s t test was utilized for analysis in c-i. Error bars represent SD (n = 3). **P ≤ 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512