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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Local application of IGFBP5 protein enhanced periodontal tissue regeneration via increasing the migration, cell proliferation and osteo/dentinogenic differentiation of mesenchymal stem cells in an inflammatory niche

Fig. 5

Local injection of rhIGFBP5 inhibited the expression of IL-1β in a minipig periodontitis model. a ELISA assay results indicated rhIGFBP5 decreased expression of IL-1β in gingival crevicular fluid. b The expression of IFNγ was not significantly different between the rhIGFBP5 group and the untreated group. One-way ANOVA was performed to determine statistical significance. Error bars represent SD (n = 6). NS no significant difference. **P ≤ 0.01. IFNγ interferon gamma, IL-1β interleukin 1 beta, NS, no significant difference. rhIGFBP5 recombinant human insulin-like growth factor binding protein 5

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Stem Cell Research & Therapy

ISSN: 1757-6512