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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2 diabetes rats

Fig. 8

UC-MSCs attenuated HFD/STZ-induced insulin resistance and inflammation in adipose tissue. (a) mRNA expression of NLRP3, IL-1β, IL-18, and TNF-α of each group. (b) IL-1β, IL-18, and TNF-α level in the blank group, T2D group, and MSC group. (c) Relative protein level of NLRP3. *P < 0.05, **P < 0.01, ***P < 0.001. DM diabetes mellitus, IL interleukin, TNF tumor necrosis factor, UC-MSC umbilical cord-derived mesenchymal stem cell

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Stem Cell Research & Therapy

ISSN: 1757-6512