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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Mesenchymal stromal cell therapy reduces lung inflammation and vascular remodeling and improves hemodynamics in experimental pulmonary arterial hypertension

Fig. 5

a Total amount of collagen in lung samples measured by colorimetric essay (Sircol™). Bars represent mean ± SD. Real-time polymerase chain reaction analysis for PC-1 (b), PC-3 (c), and transforming growth factor-β (TGF-β) (d) from lung fibroblast cell cultures. Lines represent medians, and whiskers are the interquartile range of seven animals in each group. Relative gene expression calculated as a ratio of the average gene expression level compared with the reference gene (36B4) and expressed as fold change relative to CTRL-SAL. Comparisons by Student’s t test followed by Bonferroni’s corrections for three comparisons (*p < 0.0167). CTRL control, MCT monocrotaline, SAL saline

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