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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Synergistic effects on mesenchymal stem cell-based cartilage regeneration by chondrogenic preconditioning and mechanical stimulation

Fig. 6

Gene expression in the tissue-engineered cartilage. Assays were performed after 14 days of chondrogenic differentiation under free loading (FL) or dynamic compressive loading (DL) conditions and 30 days of ectopic implantation in nude mice. Expression of chondrogenic markers (Col2a1 and Aggrecan) and hypertrophic markers (Col 10a1 and MP13) in the tissue-engineered cartilage were measured. Values represents means ± SD (n = 4). *P < 0.05, **P < 0.01, vs. MSCs + FL; # P < 0.05, vs. M-MSCs + FL; ▲ P < 0.05, vs. MSCs + DL. M-MSC manipulated mesenchymal stem cell, MSC mesenchymal stem cell

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