Fig. 11
From: Adjudin-preconditioned neural stem cells enhance neuroprotection after ischemia reperfusion in mice
Adjudin-pretreated NSCs upregulated expression of neurotrophic factors. Relative mRNA expression of BDNF, NGF, and GDNF normalized to Rplp0 in cortex (a) and striatum (b) from sham, PBS, nonpretreated NSC, and adjudin-pretreated NSC groups at 3 days after cell transplantation. Western blot analysis of BDNF in cortex (c, d) and striatum (e, f) from sham, PBS, nonpretreated NSC, and adjudin-pretreated NSC groups at 3 days after cell transplantation. Quantification of densitometric values of the protein bands normalized to β-tubulin. n = 6 in each group. Data are mean ± SEM. *P < 0.05, ***P < 0.001. BDNF brain-derived neurotrophic factor, NSC neural stem cell, PBS phosphate-buffered saline